1.2.1 - Multiplexed, Label-Free InP Nanowire Photodetectors for Nanofluidic Single-Particle Sensing
- Event
- EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich - Band
- Lectures
- Chapter
- Optical Sensors
- Author(s)
- L. Seggering, I. Fernandez-Cuesta - University of Hamburg,Hamburg (Germany), V. Flodgren, A. Das, T. K. Jensen, A. Mikkelsen - Lund University,Lund (Sweden), J. E. Sestoft, J. Nygård - University of Copenhagen,Copenhagen (Denmark)
- Pages
- 48 - 49
- DOI
- 10.5162/eurosensors2026/1.2.1
- ISBN
- 978-3-910600-12-6
- Price
- free
Abstract
We demonstrate a label-free detection of single nanoparticles using individual InP nanowires integrated into nanofluidic chips. Nanochannels confine and guide liquid and particles, while nanowires transduce optical signals into electrical ones. A single nanowire resolves the transit of sub-micrometer particles as a transient dip in its photocurrent without fluorescent labels. A modular PCB readout setup is used to read the signal from the nanowires. This system has the potential to read multiple nanowires in parallel, which can be used in the future for multiplexing and to gain insights into particle characteristics, like size and flow speed. InP nanowire, photodetector, nanofluidics, label-free detection, multiplexed readout. Background, Motivation and Objective Nanofluidic single-molecule analysis relies almost exclusively on fluorescence microscopy, which is limited to two optically aligned excitation spots per device and depends on fluorescent labelling of analytes [1]. Replacing this optical readout with an electrical one would eliminate alignment, remove labelling, and allow several sensing sites to be integrated along the same channel. Wafer-scale arrays of individually contacted InP p-i-n nanowires [2] enable a distributed electrical readout. We present a device in which nanowires, placed directly beneath a PMMA nanochannel, operate as label-free photoelectrical detectors of objects passing through the channel...