3.2.1 - Single-Cell Impedance Cytometry: Recent Progress and Challenges Ahead

Event
EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich
Band
Lectures
Chapter
Biosensors
Author(s)
F. Caselli - University of Rome Tor Vergata,Roma (Italy)
Pages
114 - 114
DOI
10.5162/eurosensors2026/3.2.1
ISBN
978-3-910600-12-6
Price
free

Abstract

A chip-sized biosensor based on lensless digital holographic microscopy is introduced for continuous, in-incubator monitoring of in vitro models. The system integrates a CMOS sensor and a micro-LED display, enabling compact, label-free imaging, and quantitative parameter extraction across biological systems. Its capabilities were validated through angiogenesis and muscle-on-chip models, enabling quantification of both morphological parameters (network formation metrics), and functional parameters (contractile displacement). This work establishes a scalable, multiparametric biosensing platform for tissue monitoring.

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