SP 2.1.2 - From Rigid to Flexible and Stretchable Hollow Microneedle Patches: Integrated Microfluidic Platforms for Dermal Inter-stitial Fluid Extraction and Intradermal Therapeutic Delivery

Event
EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich
Band
Lectures
Chapter
Continuous Health Monitoring in Medicine
Author(s)
W. Shu, T. Raicevic - ETH Zurich,Zurich (Switzerland), A. T. Güntner - ETH Zurich,Zurich (Switzerland) and University Hospital Zurich (USZ) and University of Zurich (UZH),Zurich (Switzerland)
Pages
291 - 292
DOI
10.5162/eurosensors2026/SP2.1.2
ISBN
978-3-910600-12-6
Price
free

Abstract

Dermal interstitial fluid is an attractive biofluid for minimally invasive and longitudinal biomarker monitoring. Here, we develop a flexible hollow microneedle patch that combines two-photon-polymerised hollow microneedles, an elastomeric backing layer, and soft microfluidic channels. Building on 3Dprinted microneedles integrated with silicon microfluidics, this platform improves skin conformity while maintaining reliable dermal access. Preliminary insertion, optical, and fluidic tests demonstrate effective skin interfacing, microneedle penetration, and microchannel connectivity. This mechanically compliant approach supports wearable interstitial-fluid sampling and future closed-loop sensing systems.

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