P1.1.15 Optimization of Nanostructure Size on PDMS Surface to Improve Cell Interaction

Event
14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
Nürnberg/Nuremberg, Germany
Chapter
P1.1 Biosensors
Author(s)
J. Li, Y. Hu, M. Wang - Institute of Microanalytical Systems, Department of Chemistry, Zhejiang University (China)
Pages
853 - 854
DOI
10.5162/IMCS2012/P1.1.15
ISBN
978-3-9813484-2-2
Price
free

Abstract

Anodized aluminum oxide (AAO) was used as a template to create highly ordered nanostructures on polydimethylsiloxane (PDMS) surface. The PDMS with surface nanostructures was then applied for cell analysis. It was found that the size of the nanostructure had a deep effect on cell behavior. In this work, different nanopore size AAO was created either with different electrolytes or under different anodization potential. The imprinted PDMS was then used for cell culture to find the relationship between surface nano size and cell behavior.

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