P1.3.15 A microfluidic-based PDMS prism for SPR imaging system
- Event
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
Nürnberg/Nuremberg, Germany - Chapter
- P1.3 Sensors Based on Optical Techniques
- Author(s)
- L. Zhang, X. Chen, H. Cai, H. Li, J. Sun, D. Cui - State key laboratory of transducer technology, Institute of Electronics, Chinese Academy of Sciences (China), C. Peng - Institute of Microbiology, Chinese Academy of Sciences (China)
- Pages
- 971 - 973
- DOI
- 10.5162/IMCS2012/P1.3.15
- ISBN
- 978-3-9813484-2-2
- Price
- free
Abstract
Surface plasmon resonance (SPR) is a versatile technique for label-free, high sensitive, real time detection of biomolecular binding events. The conventional SPR sensors using glass prisms, matching oil and flow cell require complex operation steps which are more suitable for a laboratory study. PDMS prism abolishes using the index matching oil or film and increases the consistency of reaction for the gold film was sputtered on it directly and it is much easier to integrate with microfluidic channels. In this paper, we developed a low-cost, convenient SPR imaging system with a microfluidic-based PDMS prism. The simulation and experiment results of imaging SPR resonant angle in the air matched with each other. We detected the air and gases breathed out by different persons that indicate the SPR imaging system have a good sensitivity to distinguish different samples.