D3.4 - Development of a Lab-on-a-Chip for Detection of Bacteria in Food Samples

Event
AMA Conferences 2013
2013-05-14 - 2013-05-16
Nürnberg
Band
Proceedings SENSOR 2013
Chapter
D3 - Cell Sensing
Author(s)
S. Mitra, D. Sarkar - University of Alberta, Edmonton (Canada), I. Jamal - AQL Management Consulting Inc., Edmonton (Canada)
Pages
525 - 530
DOI
10.5162/sensor2013/D3.4
ISBN
978-3-9813484-3-9
Price
free

Abstract

We developed an optical biosensor of nanodimensions, for the detection of bacteria in food samples, which has an integrated Mach-Zehnder Interferometer (MZI) configuration. MZI works on the principle of total internal reflection having a sensor arm, where the bacteria is to be bound by biofunctionalization, and a reference arm. The MZI is fabricated on a silicon substrate with silicon nitride (Refractive index=2.00) acting as the core and silicon dioxide (Refractive index=1.46) acting as the upper and lower cladding. Light from a laser source (He-Ne) will be coupled into the waveguide having the MZI configuration which is split into the two arms, then after a certain distance, they recombine again. This is done by using a diverging and converging Y-junction, respectively. The design of the MZI has been created using simulations in order to get a monomodal propagation of light with minimal losses. The Y-junctions have been designed so as to allow the divergence and convergence of the propagating light with a 3dB split ratio.

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