P1OS.4 - Quantitative Detection of Aminoglutethimide by Electrochemical Surface Enhanced Raman Spectroscopy
- Event
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria - Chapter
- P-1 - Optical Sensors
- Author(s)
- Z. Zhu, W. Espulgar, H. Yoshikawa, M. Saito, E. Tamiya - Osaka University, Osaka (Japan)
- Pages
- 623 - 624
- DOI
- 10.5162/IMCS2018/P1OS.4
- ISBN
- 978-3-9816876-9-9
- Price
- free
Abstract
In this work, we have investigated the detection of aminoglutethimide (AGI) drug based on its adsorption on the SERS-active screen-printed electrode employing the Electrochemical Surface-Enhanced Raman Spectroscopy (E-SERS) technology. E-SERS spectra exhibits the different absorption of AGI onto the substrate. At the -400 mV of applied potential, the E-SERS peaks of 1147 cm-1 shows the strongest intensity among the other peaks. The limit of detection (LOD) is 40 ng/mL and the square R of linear curve is 0.98. This work aims to optimize the trace detection of this drug with possible application in the deterrence and prevention of dopant usage and for point-of-care diagnostics (POCD).