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T6.2.2 - A Microfluidic Platform based on LIG Electrodes and Machine learning for Real-Time Skeletal Muscle Analysis

Event
EUROSENSORS XXXVII
2025-09-07 - 2025-09-10
Wroclaw
Band
Lectures
Chapter
T6.2 - Sensors for Medicine and Life-Sciences 2
Author(s)
G. Curci, M. Marini, J. Filippi, G. Antonelli, P. Casti, M. D’Orazio, A. Riccardi, E. Debbi, S. Pescetelli, A. Agresti, A. Mencattini, E. Martinelli - University of Rome Tor Vergata, Rome (Italy)
Pages
154 - 155
DOI
10.5162/EUROSENSORS2025/T6.2.2
ISBN
978-3-910600-07-2
Price
free

Abstract

Lab-on-chip technologies offer powerful tools for studying biological processes in physiologically rele-vant microenvironments. We present a microfluidic platform for real-time analysis of muscle contraction, uniquely integrating Laser-Induced Graphene electrodes fabricated via direct CO₂ laser engraving on polyimide tape adhered to polystyrene. This rapid, low-cost method enables precise electrical stimula-tion of muscle tissues. Time-lapse microscopy captured the resulting contractions, which were quanti-tatively analysed using machine learning algorithms to extract contractile features.

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