Tu-SFM-06 - Engineering Nanopipettes for Probing Neuronal Communication at the Nanoscale

Event

EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich

Band

Poster

Chapter

Sensor Fundamentals & Modelling

Author(s)

A. Viol, M. Aramesh, J. Vörös - ETH Zürich,Zürich (Switzerland)

Pages

684 - 685

DOI

10.5162/eurosensors2026/Tu-SFM-06

ISBN

978-3-910600-12-6

Price

free

Abstract

Nanopipettes offer a geometrically matched interface to the nanoscale structures where neuronal communication occurs, but their use as probes is limited by fundamental physical and chemical constraints. We investigate how the nanopipette–neuron interface, including probe geometry, electrolyte composition, and electrical coupling, determines both access and signal fidelity. Through controlled impalement experiments and systematic variation of recording conditions, we identify key trade-offs that govern successful measurements at this scale.