OS1.2 - A Simple Phenothiazine Based Ratiometric Fluorescent Sensor for Hypochlorite Detection
- Event
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria - Chapter
- Optical Sensors 1
- Author(s)
- D. Soni, K. Yadav, R. Chitta - Department of Chemistry, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Bandarsindri (India)
- Pages
- 89 - 90
- DOI
- 10.5162/IMCS2018/OS1.2
- ISBN
- 978-3-9816876-9-9
- Price
- free
Abstract
Hypochlorite (ClO-), an important reactive oxygen species (ROS), plays an important role in immune system. ClO- is widely used as a disinfectant for treatment of water and other household purposes. Hence there is a need to develop highly sensitive and selective molecular probes for the detection of ClO- in environmental and biological systems. Here, a simple phenothiazine based ratiometric fluorescent sensor PTZ-Ph for hypochlorite detection is presented. The detection limit of 0.36 µM was calculated. This probe was found to be selective for NaOCl as compared to other ROS, anions, and cations and also in presence of various interferents. Formation of sulfoxide was evident from the NMR titration experiment.