2025 SMSI Bannerklein

OS1.2 - A Simple Phenothiazine Based Ratiometric Fluorescent Sensor for Hypochlorite Detection

Event
17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria
Chapter
Optical Sensors 1
Author(s)
D. Soni, K. Yadav, R. Chitta - Department of Chemistry, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Bandarsindri (India)
Pages
89 - 90
DOI
10.5162/IMCS2018/OS1.2
ISBN
978-3-9816876-9-9
Price
free

Abstract

Hypochlorite (ClO-), an important reactive oxygen species (ROS), plays an important role in immune system. ClO- is widely used as a disinfectant for treatment of water and other household purposes. Hence there is a need to develop highly sensitive and selective molecular probes for the detection of ClO- in environmental and biological systems. Here, a simple phenothiazine based ratiometric fluorescent sensor PTZ-Ph for hypochlorite detection is presented. The detection limit of 0.36 µM was calculated. This probe was found to be selective for NaOCl as compared to other ROS, anions, and cations and also in presence of various interferents. Formation of sulfoxide was evident from the NMR titration experiment.

Download