OS1.4 - A low-cost plasmonic sensing device for on-site detection of diclofenac molecules
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
- Optical Sensors 1
- N. Steinke, R. Wuchrer, T. Härtling - Fraunhofer Institute for Ceramic Technologies and Systems IKTS, Dresden (Germany), G. Gerlach - Technische Universität Dresden, Institute of Solid State Electronics, Dresden (Germany)
- 93 - 94
In the field of environmental and life sciences surface plasmon resonance (SPR) sensors are wellestablished. To circumvent the current limitation of SPR sensors to applications in the laboratory environment studies on a low-cost nanostructured sensor substrate fabricated by nanoimprint lithography were conducted. The nanostructured sensor substrate is the core element for the development of a SPR-based on-site biosensor system including a novel photocurrent-based read-out approach. For this purpose, diclofenac molecules were successfully immobilized on the sensor substrates and a specific binding of an anti-diclofenac antibody with subsequent regeneration can be observed in form of a shift in the optical transmission spectra. The results show that our functionalized transducer element based on SPR is well-suited for the detection of diclofenac.