OS1.4 - A low-cost plasmonic sensing device for on-site detection of diclofenac molecules
- Event
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria - Chapter
- Optical Sensors 1
- Author(s)
- N. Steinke, R. Wuchrer, T. Härtling - Fraunhofer Institute for Ceramic Technologies and Systems IKTS, Dresden (Germany), G. Gerlach - Technische Universität Dresden, Institute of Solid State Electronics, Dresden (Germany)
- Pages
- 93 - 94
- DOI
- 10.5162/IMCS2018/OS1.4
- ISBN
- 978-3-9816876-9-9
- Price
- free
Abstract
In the field of environmental and life sciences surface plasmon resonance (SPR) sensors are wellestablished. To circumvent the current limitation of SPR sensors to applications in the laboratory environment studies on a low-cost nanostructured sensor substrate fabricated by nanoimprint lithography were conducted. The nanostructured sensor substrate is the core element for the development of a SPR-based on-site biosensor system including a novel photocurrent-based read-out approach. For this purpose, diclofenac molecules were successfully immobilized on the sensor substrates and a specific binding of an anti-diclofenac antibody with subsequent regeneration can be observed in form of a shift in the optical transmission spectra. The results show that our functionalized transducer element based on SPR is well-suited for the detection of diclofenac.