B1-b1 - Passive Cavitation Mapping of Focused Ultrasound induced Cavitation on Magnetic Nanoparticles
- Event
- 2025 ICU PADERBORN - 9th International Congress on Ultrasonics
2025-09-21 - 2025-09-25
Paderborn - Band
- Lectures
- Chapter
- B1-b - Biomedical Ultrasound for Therapy and Diagnosis
- Author(s)
- C. M. Huber, H. Ermert, S. Lyer - Universitätsklinikum Erlangen, Erlangen (Germany), I. Ullmann, M. Vossiek - Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen (Germany)
- Pages
- 146 - 149
- DOI
- 10.5162/Ultrasonic2025/B1-b1
- ISBN
- 978-3-910600-08-9
- Price
- free
Abstract
Magnetic nanoparticles (MNPs) are utilized in Magnetic Drug Targeting (MDT) to treat tumors, for which it would be advantageous to develop a monitoring method. We aim to use the cavitation produced by MNPs in a focused ultrasonic (FUS) field for imaging via passive cavitation mapping (PCM), a novel approach for MNP mapping. MNP-PCM has the advantage of real-time imaging capability and compatibility with flow conditions over other MNP imaging modalities. Additionally, cavitation can enhance perfusion and drug release. We demonstrate a PCM system for MNPs using time domain Delay and Sum (DAS); Delay Multiply and Sum (DMAS); and the Robust Capon Beamforming (RCB). The code used is available at github.com/ChristianHuber555/ICU MNP PAM.