Tu-POS-01 - Rapid Vaccine Screening and Component Analysis via a SERS Platform with Plasmonic Concentric Nanostructure Enhancers

I. -J. Chen; Y. -A. Wu; Y. -T. Cheng; H. -Y. Ko; N. -F. Chiu; K. -K. (. Kuo

Tu-POS-01 - Rapid Vaccine Screening and Component Analysis via a SERS Platform with Plasmonic Concentric Nanostructure Enhancers

Event: EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich
Band: Poster
Chapter: Photonics And Optical Sensors
Author(s): I. -J. Chen, Y. -A. Wu, Y. -T. Cheng, H. -Y. Ko, N. -F. Chiu - National Taiwan Normal University,Taipei (Taiwan), K. -K. (. Kuo - Taipei Union Hospital for Women and Children,Taipei (Taiwan)
Pages: 525 - 526
DOI: 10.5162/eurosensors2026/Tu-POS-01
ISBN: 978-3-910600-12-6
Price: free

Abstract

This study presents a highly sensitive SERS platform based on plasmonic concentric nanostructures (PCN) for rapid, label-free analysis of the Spikevax mRNA vaccine. The nanorings generate strong hotspots, enabling clear identification of mRNA, lipid nanoparticles (LNPs), and excipients (e.g., sucrose, PEG) with high reproducibility, offering an efficient tool for vaccine quality control and stability monitoring.