B2.3 - Microbiosensor-Systems for Cellular Monitoring
- SENSOR+TEST Conferences 2009
2009-05-26 - 2009-05-28
Congress Center Nürnberg
- Proceedings SENSOR 2009, Volume I
- B2 - Medical Application II
- J. Kieninger - Universität Freiburg, Freiburg, Germany
- 175 - 175
Even so, in 1885, Roux did first in vitro cultivation of embryonic egg cells, it was in the mid of last century, when animal cell cultures became routine laboratory technique. Since that time cell biologists made a lot of progress to establish in vitro models, also with different mammalian cultures, allowing research on cell physiology and metabolism as well as behaviour of the cells to different chemical compounds, e.g. for drug tests. Later on, cell culturing was used to exploit the cells, as it is done with tissue engineering. Nowadays further improvement led to the possibility of cell therapy.
Along with the progress in cell culturing, the need of peri-cellular monitoring of multiple parameters is continuously increasing. In contrast to single-shot measurements as can be performed by taking out a sample and usage of an analyzer, the monitoring allows to track the temporal behaviour of these parameters. Especially with adherent cell cultures, there is an important field and market for micro sensors to obtain sensor readings from as close to the cell layer as possible.