B3.3 - Fabrication of Microfluidic Devices Using SU-8 for Detection and Analysis of Viruses

Event
SENSOR+TEST Conferences 2009
2009-05-26 - 2009-05-28
Congress Center Nürnberg
Band
Proceedings SENSOR 2009, Volume I
Chapter
B3 - Micro Sensors
Author(s)
C. Garcia, W. Lang - University of Bremen, Bremen, Germany, A. Schomacker, I. Klarholz, C. Harms - Technologie-Transfer-Zentrum Bremerhaven, Bremerhaven, Germany
Pages
193 - 197
DOI
10.5162/sensor09/v1/b3.3
ISBN
978-3-9810993-4-8
Price
free

Abstract

A passive microfluidic device using SU-8 photoresist has been developed for detection and analysis of viruses. Due to its high aspect ratio with almost vertical sidewalls and its chemical stability, SU-8 offers a wide variety of applications in the fabrication of microfluidic systems. This photoresist is transparent allowing optical detection and thus, identification of biomolecules. Additionally, SU-8 shows a good biocompatibility offering the possibility to develop assay on the surface that allows the specific binding of biomolecules for analytical applications. In this work, the performance of the microfluidic device has been successfully demonstrated by detection of specific contaminants in test solutions. The microfluidic chip is composed of SU-8 microstructures which have been fabricated by means of photolithography, using glass and silicon as substrate materials. Beside the fabrication of microchannels by means of SU-8, we have also used SU-8 as adhesive layer.

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