6.1.4 Redox PotentialSensor Arrayby Extended-Gate FET with Ferrocenyl-Alkanethiol Modified Gold Electrode
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
- 6.1 FET- and MIP-based Sensors
- H. Anan, K. Nakazato - Department of Electrical and Computer Science, Graduate School of Engineering, Nagoya University (Japan), M. Kamahori, Y. Ishige - Central Research Laboratory, Hitachi, Ltd. (Japan)
- 523 - 526
We developed a 32×32 array chip of extended-gate FET-based redox potential sensor with 11-ferrocenyl-1-undecanethiol (11-FUT) modified gold electrode. The sensor array detected the redox reaction of hexacyanoferrate (II) and hexacyanoferrate (III) as a change in the electric potential of the 11-FUT modified electrode in accordance with the Nernstian response at a slope of 57.9 mV/decade at 25 °C with a dynamic range of more than five orders of magnitude. The stability of the potential was within 0.5 mV/h. Of all 32×32 sensor cells, each potential of 80% and each difference of 92% were within ± 5 mV and ± 1 mV from median, respectively. The 2-dimensional and real time visualization were enabled by imaging of sensor array. Using an enzyme-catalyzed redox reaction, this FETbased sensor array successfully detected a glucose level from 25 to 200 mg/dL.