DH1.2 - Thermal biomimetic sensing as a tool for point-of-care bacteria detection
- Event
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria - Chapter
- Sensors for Diagnostics and Health Care 1
- Author(s)
- K. Eersels, B. van Grinsven, R. Rogosic, J. Lowdon, B. Heidt, H. Diliën, E. Steen Redeker, T. Cleij - Maastricht University, Maastricht Science Programme, Maastricht (The Netherlands), M. Peeters - Manchester Metropolitan University, Faculty of Science & Engineering, Div. of Chemistry & Environmental Science, Manchester (United Kingdom), P. Cornelius, P. Wagner - KU Leuven, Department of Physics and Astronomy, Soft-Matter Physics and Biophysics Section, Leuven (Belgium)
- Pages
- 113 - 114
- DOI
- 10.5162/IMCS2018/DH1.2
- ISBN
- 978-3-9816876-9-9
- Price
- free
Abstract
This work introduces a novel bacterial identification assay based on thermal wave analysis through surface-imprinted polymers (SIPs). A novel thermal sensing platform; coined thermal transport analysis (TWTA) that has been previously used for the detection of dopamine in banana juice was combined for the first time with SIPs. The technique, based on the analysis of a propagation of a thermal wave through functionalized surfaces, has previously been shown to be more sensitive than the previously developed heat-transfer method. SIP-coated aluminum chips were imprinted with Escherichia coli and used for the detection of bacteria in spiked urine samples. The proposed sensor platform was able to detect bacteria in concentration regimes relevant for urinary tract diagnosis (UTI), illustrating the diagnostic potential of the thermal detection platform and its combination with synthetic receptors.