BS4.4 - TiO2 Nanorod-based Photoelectrochemical Sensor for Alzheimer's Disease Detection

Event
17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria
Chapter
Biosensors 4 - Novel Transducers
Author(s)
C. Yang, L. Wang - Institute of Electro-Optical Engineering, Chang Gung University, Taoyuan (Taiwan), H. Liu - Department of Electronic Engineering, Chang Gung University, Taoyuan (Taiwan), Y. Lu - Department of Neurosurgery, Chang Gung Memorial Hospital Linkou Medical Center and College of Medicine, Chang Gung University, Taoyuan (Taiwan), C. Chen - Sustainable Energy Development Center, National Taiwan University of Science and Technology, Taipei (Taiwan), L. Chen - Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei City (Taiwan)
Pages
184 - 185
DOI
10.5162/IMCS2018/BS4.4
ISBN
978-3-9816876-9-9
Price
free

Abstract

In this research. TiO2 nanorods was fabricated on FTO/glass as electrode for the immobilized of Alzheimer’s disease antibody by using 3-mercaptopropionic acid (MPA). Then, cyclic voltammetry method was used to test the current response to Alzheimer’s disease peptide. The result shows that biggest change of current could nearly 2 μA. The light on/off cycle of illumination by LED with different wavelength was performed in Faraday cage to evaluate the photo response. With illumination by wavelength of 470 nm could have an acceptable photocurrent, which could have less damage to biorelated spices comparing to UV illumination. 15% increases of current could be achieved by this illumination on TiO2 nanorod. , which is proven for larger signal for Alzheimer’s disease detection.

Download