SM1.3 - Microfluidic biomimetic sensor for drug detection
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
- Sensor Systems and Microfluidics 1
- R. Rogosic, B. van Grinsven, K. Eersels, J. Lowdon, B. Heidt, H. Dilien, E. Steen Redeker, T. Cleij - Maastricht University, Maastricht (The Netherlands), M. Peeters - Manchester Metropolitan University, Faculty of Science & Engineering, Div. of Chemistry & Environmental Science, Manchester (United Kingdom), P., P. Cornelis, P. Wagner - KULeuven, Department of Physics and Astronomy, Soft-Matter Physics and Biophysics Section, Leuven (Belgium)
- 368 - 369
The work presented in this study, focuses on the biomimetic detection of narcotics in biological fluids. To this extent, a previously developed thermal biosensor readout unit was combined with sensitive nano-sized molecularly imprinted polymer (MIP) particles. The platform has recently been combined with disposable, microfluidic flow cells for the detection of neurotransmitters in whole blood samples in physiological concentrations. In this work, the concept was extended by developing a new microfluidic flow cell containing 6 measuring chambers connected to a single fluid inlet. Administering a drop of blood to the central inlet, distributes the drop over the entire flow cell, allowing the end-user to detect five different narcotic substances in a differential manner.