P2BM.3 - Development of whole blood vancomycin sensor using electrode grafted molecularly imprinted polymer
- Event
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria - Chapter
- P-2 - Biomimetic Sensors
- Author(s)
- H. Eguchi, Y. Yoshimi - Shibaura Institute of Technology, Tokyo (Japan), A. Hatano - Shibaura Institute of Technology, Saitama (Japan)
- Pages
- 690 - 691
- DOI
- 10.5162/IMCS2018/P2BM.3
- ISBN
- 978-3-9816876-9-9
- Price
- free
Abstract
Therapeutic drug monitoring (TDM) is strongly recommended for vancomycin (VCM), which is the firstline antibacterial agent against hospital-acquired infection. However, the conventional vancomycin analysis method is cumbersome in operation and forced to outsource inspection to external organizations, so the time lag of TDM is too long to for preventing resistant-bacteria creation. Therefore, we developed a vancomycin sensor for TDM which can measure rapidly and conveniently using molecularly imprinted polymer (MIP) which has a specific binding ability and can be produced easily and economically. In this study, we investigated the polymerization conditions and operating conditions and attempted to develop a vancomycin sensor showing high sensitivity in whole blood.