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TP65 - Electrochemical detection of cortisol using carbon nano-tubes (CNT) modified with a pyrene derivative

Event
EUROSENSORS XXXVII
2025-09-07 - 2025-09-10
Wroclaw
Band
Poster II
Chapter
Sensors for Medicine and Life-Sciences
Author(s)
A. R. Santos, B. Faria, M. C. Paiva, J. C. Viana, A. F. Silva - University of Minho, Guimarães (Portugal), F. Bento - Chemistry Research Centre of the University of Minho, Braga (Portugal)
Pages
484 - 485
DOI
10.5162/EUROSENSORS2025/TP65
ISBN
978-3-910600-07-2
Price
free

Abstract

Constant high cortisol levels resulting from chronic stress impair mental health and performance, yet real-time monitoring remains challenging. For non-invasive analysis, an electrochemical cortisol sensor was developed using carbon nanotubes (CNTs) non-covalently functionalized with pyrene derivatives (PY). Functionalized CNTs enabled cortisol interaction, with sensitivity and dynamic range evaluated through differential pulse voltammetry (DPV). Molecular dynamics (MD) simulations further clarified cor-tisol–pyrene interactions. This approach lays the groundwork for simple, non-invasive stress monitoring.

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