Mo-MLO-01 - Full-Hydrogel-based Real-Time Sensor and Drug Deliverer in Organ-on-Chip Devices
- Event
- EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich - Band
- Poster
- Chapter
- Microfluidic Devices, Lab on a Chip, µTAS, Organ on Chip Systems
- Author(s)
- G. Antonelli, E. Debbi, F. Corsi, A. Idili, A. Mencattini, E. Martinelli - University of Rome Tor Vergata,Rome (Italy)
- Pages
- 487 - 488
- DOI
- 10.5162/eurosensors2026/Mo-MLO-01
- ISBN
- 978-3-910600-12-6
- Price
- free
Abstract
Integrating sensors into Organ-on-Chip devices is a crucial step toward fully exploiting these powerful platforms for biomedical research, especially in drug development. In this work, we used a custom stereolithography setup to embed hydrogels within a low-cost thermoplastic Organ-on-Chip. These micrometric hydrogels could absorb the drug, permitting a controlled release during the experiment. Moreover, the absorbed drugs acquired intrinsic fluorescence, which was exploited to train a machine learning algorithm, enabling quantitative tracking of absorption and release during the experiment.