Mo-SMD-01 - A Miniaturized Electrochemical Biosensor for Real-Time In Vivo Potassium Monitoring in the Inner Ear

Event

EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich

Band

Poster

Chapter

Sensing For Medical Diagnostics And Monitoring

Author(s)

F. Arshadi, M. Esfandiari, C. Pastras, M. Asadnia - Macquarie University,Sydney (Australia), R. Gay, Y. L. Enke - Cochlear Limited,Sydney (Australia), N. Farbehi - University of New South Wales,Sydney (Australia)

Pages

586 - 587

DOI

10.5162/eurosensors2026/Mo-SMD-01

ISBN

978-3-910600-12-6

Price

free

Abstract

This work presents a miniaturized potassium-selective biosensor for continuous in vivo potassium monitoring in the inner ear, addressing an important need in medical diagnostics. The platform integrates a potassium-selective electrode with a stable Ag/AgCl reference electrode and demonstrates high sensitivity, selectivity, a broad detection range, and long-term stability. Benchtop validation confirmed reliable electrochemical performance. In vivo experiments in a guinea pig model further demonstrated the sensor’s ability to detect real-time potassium fluctuations under physiological conditions. This technology may provide a foundation for real-time ionic monitoring in preclinical inner ear research. The findings suggest that potassium could serve as a promising biomarker of cochlear health and may support the future development of implantable sensing platforms for continuous monitoring and improved management of inner ear disorders.