Mo-SMD-04 - High-Sensitivity Electrochemical Detection of Point Mutations: Optimization of BRAF V600E Analysis from Liquid Biopsy

Event

EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich

Band

Poster

Chapter

Sensing For Medical Diagnostics And Monitoring

Author(s)

L. Moráňová - Masaryk Memorial Cancer Institute,Brno (Czech Republic), K. Itterheimová, J. Strmisková - National Center for Biomolecular Research - Masaryk University,Brno (Czech Republic) and Masaryk Memorial Cancer Institute,Brno (Czech Republic), M. Bartošík - Masaryk Memorial Cancer Institute,Brno (Czech Republic)

Pages

592 - 593

DOI

10.5162/eurosensors2026/Mo-SMD-04

ISBN

978-3-910600-12-6

Price

free

Abstract

We introduce a headspace sampling setup for longitudinal monitoring of volatile emissions from microbial species that is compatible with various sensor methodologies. The setup was validated using mass spectrometry and chemoresistive sensors, showing reliable extraction with gas standards and Escherichia coli isolates over 24 h. Results show bacterial metabolic activity is mirrored in headspace volatile concentrations, with acetaldehyde serving as a key proliferation indicator. This proof-of-concept system enables continuous monitoring for rapid pathogen detection and antibiotic susceptibility evaluation.