Mo-SMD-03 - Engineering Spatially Patterned Selective Membranes for Scalable Multiplex Electrolyte Sensors

Event

EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich

Band

Poster

Chapter

Sensing For Medical Diagnostics And Monitoring

Author(s)

A. Nilghaz, N. H. Voelcker - Monash University,Parkville (Australia), C. Devendran - Proton Intelligence Australia Pty Ltd,Clayton (Australia)

Pages

590 - 591

DOI

10.5162/eurosensors2026/Mo-SMD-03

ISBN

978-3-910600-12-6

Price

free

Abstract

This study presents electrochemical approaches for detecting the BRAF V₆₀₀E mutation in circulating tumor DNA (ctDNA) from liquid biopsies. The V₆₀₀E mutation was successfully identified in clinical samples using SNP-specific primers in Loop-mediated isothermal amplification (LAMP). Additionally, a novel strategy employing CRISPR/Cas12a cleavage to selectively degrade wild-type (WT) sequence was evaluated to enhance mutation-specific detection.