P2EC.5 - Electrochemical discrimination of dopamine and its metabolites at fluorine-doped tin oxide
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
- P-2 - Electrochemical Sensors
- G. Göbel, F. Lisdat - Biosystems Technology, Institute of Applied Life Sciences, Technical University of Applied Sciences, Wildau (Germany)
- 711 - 712
Dopamine and other catecholamines are involved in numerous processes in the neuronal network. Various methods for their analysis have been developed. In order to avoid a disturbance of sensor signal by interfering substances electrochemical sensors for catecholamines apply frequently complex modification strategies. These sensors are characterized often by a rather poor signal stability because of the deposition of polymerization products at the electrode surface. Fluorine-doped tin oxide (FTO) as electrode material allows the direct detection of dopamine via differential pulse voltammetry without expensive modifications and stability problems. This kind of electrode material can discriminate between dopamine and metabolites, is characterized by a wide linear range, shows a high stability of the sensor signal and is not disturbed by typical interfering substances (ascorbic acid, uric acid).