Tu-BBS-16 - Biochemical Modulation of Ionic Transport in Asymmetric Nanochannels for Label-Free Biosensing

Event

EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich

Band

Poster

Chapter

Biosensors/-electronics And Biomimetic Sensors

Author(s)

L. M. Hernandez Parra, W. Marmisollé, O. Azzaroni, M. L. Cortez - Universidad Nacional de La Plata (UNLP),La Plata (Argentina), M. E. Toimil-Molares - GSI Helmholtzzentrum für Schwerionenforschung,Darmstadt (Germany) and Technische Universität Darmstadt,Darmstadt-West (Germany)

Pages

388 - 389

DOI

10.5162/eurosensors2026/Tu-BBS-16

ISBN

978-3-910600-12-6

Price

free

Abstract

Biomimetic solid-state asymmetric nanochannels serve as platforms for the integration of enzymes and functional polymers. Enzymatic reactions generate localized pH variations at the nanochannel surface, which are transduced by polymeric layers into measurable changes in iontronic current through acid–base-dependent modulation of surface charge within the multilayer assembly. The asymmetric bullet-shaped nanochannel geometry enhances the sensing response through nanoconfinement effects and amplified ionic current rectification, providing a promising strategy for the development of label-free biosensing platforms.