P1.9.21 Design and fabrication of Passive Fluid Driven Microchannel for Fast Reaction Assays in Nano lab-on-chip Domain
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
- P1.9 Technology and Application
- T. Adam, U. Hashim - Institute Nano Electronic Engineering, Universiti Malaysia Perlis. (UniMAP) (Malaysia), P. Leow, S. Che Harun - Faculty of Electrical Engineering, Universiti Teknologi Malaysia (UTM) (Malaysia)
- 1223 - 1226
A simple design for a microfluidic flow system for use in reacting assays with limited sample availability has been proposed, analyzed using COMSOL 3.5 Multiphysics simulation and fabricated using soft-lithography technique. The design is based on differential pressure drop flow using capillary effect concept which has facilitated a number of interesting flow phenomena in micro-domains. For an average pressure drop of about 100/m in the setup, flow rates of bout 0.7 to 1 µl/s were obtained. The component consists of a microchannel, three designs were tested (50, 70, 90 microns in width) to give a continuous open circuit flow. The system was designed and fabricated for continuous flow across sensing element where there is a requirement for low residence time due to fast reaction/diffusion rates.