FE.6 - Development of Stable ISFETs for Salivary Nitrate to Acute Stress Monitoring
- Event
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria - Chapter
- Field-Effect Sensors
- Author(s)
- S. Wakida, S. Osaki, T. Kintoki, K. Kitamura - AIST PhotoBIO-OIL, National Institute of Advanced Industrial Science and Technology (AIST), Osaka (Japan), K. Murai - Graduate School of Maritime Sciences, Kobe University, Kobe (Japan)
- Pages
- 433 - 434
- DOI
- 10.5162/IMCS2018/FE.6
- ISBN
- 978-3-9816876-9-9
- Price
- free
Abstract
We studied stable nitrate ion-selective field-effect transistors (ISFETs) to detect human salivary nitrate using direct potentiometry. We investigated several biocompatible polymer based nitrate ISFETs as polymer matrix material. The prepared NO3--ISFETs showed almost the theoretical Nernst response over 10-5.5 M to 10-0.5 M with a response time of less than a few seconds except for Tecoflex®. As we applied whole human saliva using direct potentiometry, we obtained good relationship with conventional ion chromatography in case of KP-13 based ISFETs. We will also introduce several acute stress subjects for healthy volunteers using wearable heart rate monitor and salivary nitrate by prototype of nitrate FET checkers.