P2.2.2 Integrating Segmented Strip Microfluidic Device with Surface plasmon resonance sensor for IFN-r detection

Event

14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
Nürnberg/Nuremberg, Germany

Chapter

P2.2 Resonant Sensors

Author(s)

T. Chuang, C. Chang, C. Lin - Institute of Biomedical Engineering, National Taiwan University (Taiwan)

Pages

1407 - 1409

DOI

10.5162/IMCS2012/P2.2.2

ISBN

978-3-9813484-2-2

Price

free

Abstract

In this study, we integrated segmented strip microfluidic device with surface plasmon resonance (SPR) sensor to realize an end-point assay for detecting IFN-_ that is critical for Mycobacterium tuberculosis infection. With the DNA probe, we were able to specifically detect the IFN-_ at the concentration of 0.01 nM within 25 min. It has the potential for fast diagnosis test and was used for on-site deployment based on nitrocellulose membrane and segmented membrane design to regulate the flow rate during measurement process.