P2.2.2 Integrating Segmented Strip Microfluidic Device with Surface plasmon resonance sensor for IFN-r detection
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
- P2.2 Resonant Sensors
- T. Chuang, C. Chang, C. Lin - Institute of Biomedical Engineering, National Taiwan University (Taiwan)
- 1407 - 1409
In this study, we integrated segmented strip microfluidic device with surface plasmon resonance (SPR) sensor to realize an end-point assay for detecting IFN-_ that is critical for Mycobacterium tuberculosis infection. With the DNA probe, we were able to specifically detect the IFN-_ at the concentration of 0.01 nM within 25 min. It has the potential for fast diagnosis test and was used for on-site deployment based on nitrocellulose membrane and segmented membrane design to regulate the flow rate during measurement process.