P2.2.4 Electrochemical-Surface Plasmon Resonance Sensor for the Detection of Adrenaline on Poly(2-aminobenzylamine) Thin Film
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
- P2.2 Resonant Sensors
- S. Chuekachang, R. Janmanee, A. Baba, S. Sriwichai, K. Shinbo, K. Kato, F. Kaneko - Center for Transdisciplinary Research and Graduate School of Science and Technology, Niigata University (Japan), S. Phanichphant - Materials Research Science Center, Faculty of Science, Chiang Mai University (Thailand), N. Fukuda, H. Ushijima - National Institute of Advanced Industrial Science and Technology (Japan)
- 1414 - 1417
Catecholamines (CA) are molecules that have a catechol or 3,4-dihydroxylphenyl group and an ethylamine, which found in the sympathetic nervous system and response to mental stress. They include dopamine, adrenaline and noradrenaline. Development and optimization of methods for the high specific and selective determination of catecholamines are of important significance. In this research, poly (2-amino-benzylamine) (P2ABA) has been used to detect adrenaline. P2ABA is a polyaniline-based polymers, which has a good conductivity and stability when doping in neutral PBS solution. Furthermore, P2ABA has a benzylamine group in the structure which can specifically react with adrenaline and has a specific reaction site in the structure. The P2ABA thin film was prepared by electropolymerization of 2-aminobenzylamine monomer on a gold-coated high reflective index glass substrate. The P2ABA thin film formation on the gold electrode was studied by electrochemial surface plasmon resonance spectroscopy (EC-SPR) spectroscopy. QCM-D was also investigated for the specific reaction of adrenaline with the P2ABA thin film.