P1BS.9 - Bacteria capture using artificial magnetic cilia
- Event
- 17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria - Chapter
- P-1 - Biosensors
- Author(s)
- P. Hesketh, S. Hanasoge, A. Alexeev - Woodruff School of Mechanical Engineering, Georgia Tech, Atlanta, GA (USA), Y. Ortega, M. Erikson - College of Agricultural and Environmental Sciences, University of Georgia, Griffin, GA (USA)
- Pages
- 491 - 492
- DOI
- 10.5162/IMCS2018/P1BS.9
- ISBN
- 978-3-9816876-9-9
- Price
- free
Abstract
Microorganisms use hair like cilia on their surface to perform many biophysical functions. Most important among them is the feeding mechanism, in which the organism creates fluid flow to trap particles and feed on them. Natural cilia are also used to sort particles before feeding. In this work, we demonstrate artificial cilia capable of capturing particles in a microfluidic device. Elastic NiFe thin filaments are used as cilia, which extend away from the substrate. The bio-mimetic oscillations of the cilia, enhances fluid mixing and therefore increases the probability of particle capture. This can be particularly useful for target pre-concentration and detection of species of interest. We demonstrate the capture of salmonella bacteria on the surface of the cilia, which is functionalized with antisalmonella. This target specific antibody enables specific capture of salmonella bacteria in a given sample. In general, a similar technique as demonstrated here can be used to capture any specific target.