3.3.5 - Microfluidic Integration of Interfacial Nanopores for Single-Molecule Sensing under FPGA-Based Closed-Loop Control
- Event
- EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich - Band
- Lectures
- Chapter
- Physical Sensors
- Author(s)
- L. Petrella, L. Dysli, J. Imfeld, J. N. Cronk, M. Aramesh - ETH Zürich,Zürich (Switzerland)
- Pages
- 130 - 131
- DOI
- 10.5162/eurosensors2026/3.3.5
- ISBN
- 978-3-910600-12-6
- Price
- free
Abstract
We present interfacial nanopores integrated into microfluidic devices as a versatile platform for singlemolecule sensing in small-volume samples. On-chip integration combined with FPGA-based closedloop control enables leak-free, mechanically stable nanopore formation with tunable resistance up to the hundred megaohm range. Initial tests on double-stranded DNA demonstrate the working principle, with single-cell secretomics envisioned as the target application.