8.2.1 - On-Chip Label-Free Holographic NTA for Biophysical Characterization of Single Particles
- Event
- EUROSENSORS 2026
2026-09-06 - 2026-09-09
Zurich - Band
- Lectures
- Chapter
- Physical Sensors
- Author(s)
- C. Lombardo, B. Vignon, J. Ortega Arroyo, R. Quidant - ETH Zürich (Switzerland)
- Pages
- 256 - 257
- DOI
- 10.5162/eurosensors2026/8.2.1
- ISBN
- 978-3-910600-12-6
- Price
- free
Abstract
We present an integrated optofluidic platform combining off-axis holographic microscopy with microfluidics for label-free tracking and characterization of heterogeneous nanoparticles. It extends tracking volumes and uses scattering contrast to simultaneously determine the size and refractive index of freely diffusing nanoparticles. We successfully classified synthetic nanoparticles and characterized biological ones without prior labeling.