C1.3 - Human Serum from Kidney Cancer Patients Analyzed with a New Sensitive Fast Liquid Differential Scanning Calorimetry Sensor
- AMA Conferences 2015
2015-05-19 - 2015-05-21
- Proceedings SENSOR 2015
- C1- MEMS Applications
- R. Splinter, A. A.W. van Herwaarden - Xensor Integration BV, Delfgauw (The Netherlands) , S. Pastorekova - Slovak Academy of Sciences, Bratislava (Slovak Republic)
- 352 - 355
Differential Scanning Calorimetry is being investigated as an analytical tool to detect cancer and other diseases by measuring the heat induced protein denaturation in blood plasma. This paper presents a much faster alternative method by using chip-based Fast Differential Scanning Calorimetry. Compared to standard Differential Scanning Calorimetry Fast Differential Scanning Calorimetry is able to reduce measurement time from hours to seconds. The latest development, a more sensitive chip has been tested with healthy control blood serum and blood serum from kidney cancer patients. Clear differences between the control serum and the serum from the cancer patients are found.